Thermo Fisher Scientific MEP1B Polyclonal Antibody
MEP1B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. 인간 MEP1B(aa 480-652) 서열 기반 항원으로 제작되었으며, 고순도 친화 크로마토그래피 정제 및 PBS/glycerol 저장 buffer를 사용합니다. 연구용 전용 제품입니다.
- 카탈로그번호
- PA587627
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MEP1B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 480–652 of human MEP1B (NP_0059162) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804300 |
Product Specific Information
Immunogen sequence:
ISGANDDQLQ WPCPWQQATM TLLDQNPDIR QRMSNQRSIT TDPFMTTDNG NYFWDRPSKV GTVALFSNGT QFRRGGGYGT SAFITHERLK SRDFIKGDDV YILLTVEDIS HLNSTQIQLT PAPSVQDLCS KTTCKNDGVC TVRDGKAECR CQSGEDWWYM GERCEKRGST RDT
Positive Samples: Mouse kidney
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
Meprins are multidomain zinc metalloproteases highly expressed in mammalian kidney and intestinal brush border membranes, leukocytes, and certain cancer cells. They hydrolyze various peptide and protein substrates and are implicated in cancer and intestinal inflammation. Mature meprins form oligomers of alpha and/or beta subunits: alpha homooligomers are secreted, while beta-containing oligomers are membrane-bound. The MEP1B gene encodes the beta subunit, and its disruption in mice affects embryonic viability and renal gene expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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