Thermo Fisher Scientific Phospho-Androgen Receptor (Ser792) Polyclonal Antibody
인간, 마우스, 랫트에서 인산화된 Androgen Receptor(Ser792)를 검출하는 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 액상 형태로 제공됩니다. PBS/50% glycerol buffer에 보존되어 -20°C에서 안정적으로 저장 가능합니다.
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Thermo Fisher Scientific Phospho-Androgen Receptor (Ser792) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human AR (Accession P10275), corresponding to amino acid residues around phosphorylated Ser792 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817513 |
Product Specific Information
This antibody detects endogenous levels of Androgen Receptor only when phosphorylated at Ser792.
Target Information
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. It is a ligand-activated transcription factor that binds testosterone (T) and dihydrotestosterone (DHT). Upon ligand binding, AR translocates to the nucleus, dimerizes, and activates transcription of androgen-responsive genes. AR signaling is essential for development and function of male reproductive organs (e.g., prostate, epididymis) and also plays roles in muscle, hair follicles, and brain. AR is a phosphoprotein that interacts with MAP kinase pathways. Dysregulation of AR signaling is associated with diseases such as prostate cancer, Kennedy's disease, and male infertility. Mutations in AR can lead to complete androgen insensitivity (CAIS).
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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