Thermo Fisher Scientific CD34 Monoclonal Antibody (1H6), PE
Thermo Fisher의 CD34 단클론 항체(1H6), PE는 개(Canine) CD34 단백질을 표적하는 Mouse IgG1 항체로, 유세포분석(Flow Cytometry)에 적합합니다. PE 형광 표지로 565/576 nm에서 여기/방출되며, 동결건조 형태로 제공되어 재구성 후 4°C에서 보관 가능합니다.
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Applications
- Flow Cytometry (Flow): Neat dilution tested
- Referenced in 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Published Species | Dog |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | Canine CD34 fusion protein |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2074487 |
Additional Formats
- Biotin (Cat. MA5-28354)
- FITC (Cat. MA1-81639)
- Custom conjugation available upon request
Product Specific Information
- Reconstitute with 1 mL of distilled water.
- After reconstitution, store undiluted at 4°C in the dark.
- Shelf life after reconstitution: approximately 18 months.
- For FACS analysis: use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
- Mouse anti-dog CD34 antibody (clone 1H6) recognizes the canine homologue of CD34, a glycosylated type I transmembrane protein (~110 kDa) expressed on endothelial and hematopoietic stem cells.
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) expressed on many stem cell populations. It functions as a stem cell marker and may regulate adhesion, differentiation, and proliferation of hematopoietic stem and progenitor cells. CD34 could act as an adhesion molecule mediating attachment of stem cells to the bone marrow extracellular matrix or stromal cells. It may also serve as a scaffold for lineage-specific glycans, facilitating binding to lectins expressed by marrow components. The intracellular domain is a phosphorylation site for protein kinase C, suggesting a role in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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