Thermo Fisher Scientific SGK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 228-367 of human SGK2 (NP_7337941) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SGK2,uniProtId:Q9HBY8-2,ncbiNodeId:9606,antigenRange:228-367,antigenLength:367,antigenImageFileName:PA5-88372_SGK2_Q9HBY8-2_Rabbit.svg,antigenImageFileNamePDP:PA5-88372_SGK2_Q9HBY8-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.41 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804865

Product Specific Information

Immunogen sequence: LHGLPPFYSQ DVSQMYENIL HQPLQIPGGR TVAACDLLQS LLHKDQRQRL GSKADFLEIK NHVFFSPINW DDLYHKRLTP PFNPNVTGPA DLKHFDPEFT QEAVSKSIGC TPDTVASSSG ASSAFLGFSY APEDDDILDC; Positive Samples: BxPC-3, 293T; Cellular Location: Cytoplasm, Nucleus

Target Information

SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.