Thermo Fisher Scientific Human IgG4 Recombinant Rabbit Monoclonal Antibody (ST05-12)
인간 IgG4를 인식하는 재조합 토끼 단일클론 항체로, 높은 특이성과 재현성을 제공합니다. Western blot 및 IHC(P) 실험에 적합하며, Protein A로 정제된 액상 형태입니다. 연구용으로 면역반응 및 자가면역 질환 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ST05-12 |
| Immunogen | Synthetic peptide within Human IgG4 (aa 85–129) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809458 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
Human IgG4 (immunoglobulin G4) is a subclass of human IgG antibodies, the least abundant in blood. It binds to antigens and promotes their clearance through mechanisms such as phagocytosis and complement activation. IgG4 also plays roles in immune tolerance and inflammation suppression.
Human IgG4 is used in research to study immune responses and to develop diagnostic and therapeutic tools for infectious and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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