Thermo Fisher Scientific Phospho-Calmodulin 1/2/3 (Thr80, Ser82) Polyclonal Antibody
Calmodulin 단백질의 Thr80 및 Ser82 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응. PBS+50% glycerol 용액 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CALM1 (Accession P0DP23), corresponding to amino acid residues around phosphorylated Ser82. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816405 |
Product Specific Information
This antibody detects endogenous levels of Calmodulin 1/2/3 only when phosphorylated at Thr80 and Ser82 (historically referenced as Thr79 and Ser81).
Target Information
Calmodulin is a small, highly conserved calcium-binding protein found in all eukaryotic cells. It can bind up to four calcium ions and serves as a key intracellular receptor for regulatory calcium signals. Upon calcium binding, calmodulin undergoes conformational changes that increase its affinity for target proteins. It regulates numerous biological processes, including:
- Energy and biosynthetic metabolism
- Cell motility and exocytosis
- Cytoskeletal assembly
- Intracellular modulation of cAMP and calcium concentrations
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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