Thermo Fisher Scientific TUBA1B Monoclonal Antibody (OTI3H2), TrueMAB
인간 TUBA1B 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. PBS 버퍼(8% 트레할로스)로 안정화되어 있으며 보존제 무첨가. 연구용으로 세포 내 미세소관 연구에 활용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H2 |
| Immunogen | Full length human recombinant protein of human TUBA1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Microtubules are dynamic intracellular polymers composed of conserved alpha/beta-tubulin heterodimers and microtubule-associated proteins (MAPs).
They are essential for key cellular processes such as mitosis, meiosis, maintenance of cell shape, intracellular transport, and cell motility via flagella and cilia.
In mammalian cells, microtubules are anchored at microtubule organizing centers (MTOCs). Tubulin polymerization is GTP-dependent and exhibits dynamic instability, where microtubules alternately grow and shrink.
Alpha-tubulin (~50 kDa) exists as part of soluble dimers or polymerized microtubules. In humans, six genes encode alpha-tubulin isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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