Thermo Fisher Scientific NDUFS1 Polyclonal Antibody
NDUFS1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol buffer 제공. 연구용으로만 사용.
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Thermo Fisher Scientific NDUFS1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 80–290 of human NDUFS1 (NP_004997.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914079 |
Product Specific Information
Positive test controls include:
- Raji
- NCI-H460
- PC-3
- Mouse heart
- Mouse intestine
The target is typically localized to the mitochondrion inner membrane.
Immunogen sequence:
VEIEKAPKVV AACAMPVMKG WNILTNSEKS KKAREGVMEF LLANHPLDCP ICDQGGECDL QDQSMMFGND RSRFLEGKRA VEDKNIGPLV KTIMTRCIQC TRCIRFASEI AGVDDLGTTG RGNDMQVGTY IEKMFMSELS GNIIDICPVG ALTSKPYAFT ARPWETRKTE SIDVMDAVGS NIVVSTRTGE VMRILPRMHE DINEEWISDK T
Target Information
The protein encoded by the NDUFS1 gene is part of the complex I 75 kDa subunit family. Mammalian complex I consists of 45 different subunits and is located in the mitochondrial inner membrane.
This protein has NADH dehydrogenase and oxidoreductase activity, transferring electrons from NADH to the respiratory chain, with ubiquinone as the electron acceptor.
It is the largest subunit of complex I and a component of the iron-sulfur fragment, possibly forming part of the active site where NADH is oxidized.
Mutations in NDUFS1 are associated with complex I deficiency. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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