Thermo Fisher Scientific TGIF Polyclonal Antibody
TGIF 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 250–340 of human TGIF1 (NP_733796.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.14 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914087 |
Product Specific Information
Positive test controls include: HepG2, MCF7, K-562, U-251MG, Mouse liver, Mouse testis, Rat uterus.
Immunogen sequence:
SSVESVMGIK NFMPALEETP FHSCTAGPNP TLGRPLSPKP SSPGSVLARP SVICHTTVTA LKDVPFSLCQ SVGVGQNTDI QQIAAKNFTD T
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. TGIF acts as a transcriptional co-repressor of SMAD2 and may participate in nuclear signaling during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, a structural brain anomaly.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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