Thermo Fisher Scientific MIP-3 alpha Monoclonal Antibody (114906)
마우스 MIP-3α(CCL20)를 인식하는 Rat IgG1 단일클론 항체. Western blot 검증 완료. 단백질 A/G로 정제된 동결건조 형태로 제공. PBS(5% trehalose) 완충액에 재구성 가능하며, 연구용으로만 사용.
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Applications and Tested Dilution
- Western Blot (WB): 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 114906 |
| Immunogen | E. coli-derived recombinant mouse CCL20/MIP-3 alpha (Ala28–Met97) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609977 |
Product Specific Information
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Macrophage Inflammatory Protein-3 alpha (MIP-3α), also known as CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes.
It is upregulated by inflammatory signals and downregulated by the anti-inflammatory cytokine IL-10.
MIP-3α signals through the G protein-coupled receptor CCR6, acting as a chemoattractant for lymphocytes and dendritic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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