Thermo Fisher Scientific ERBB2 Monoclonal Antibody (OTI4G10), TrueMAB
ERBB2 단백질을 인식하는 고특이성 Mouse Monoclonal Antibody로, Western blot, IHC, ICC/IF에 적합. Lyophilized 형태로 제공되며, 인체 HER2 단백질(aa 676–1255)을 면역원으로 제작. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 676–1255 of human ERBB2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase overexpressed in certain breast tumors. Herceptin, used in treatment of metastatic HER2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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