Thermo Fisher Scientific CKI alpha Polyclonal Antibody
Human CKI alpha 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합. Antigen affinity chromatography로 정제되어 높은 특이성과 재현성 제공. 4°C 보관, 연구용 전용.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 287 and 337 of human casein kinase 1 alpha 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
This kinase phosphorylates a large number of proteins and participates in Wnt signaling. It phosphorylates CTNNB1 at Ser-45 and may phosphorylate PER1 and PER2. It may also play a role in chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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