Thermo Fisher Scientific CKI alpha Polyclonal Antibody
Rabbit polyclonal antibody recognizing CKI alpha (CSNK1A1). Validated for WB and IP applications. Targets residues 287–337 of human CKI alpha 1. Supplied as a liquid, unconjugated form, 0.20 mg/mL concentration. Recommended storage at 4°C, shipped on w...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 287 and 337 of human casein kinase 1 alpha 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Mouse.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, encoding serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and found in nuclei, cytoplasm, and membranes of eukaryotic cells.
They phosphorylate numerous proteins and are involved in Wnt signaling, phosphorylating CTNNB1 at Ser-45, and may also phosphorylate PER1 and PER2. CKI alpha may play a role in chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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