Thermo Fisher Scientific Dopamine D2 Receptor, Polyclonal Antibody
Rabbit polyclonal antibody specific to Dopamine D2 Receptor (DRD2). Validated for WB, IHC-P, and ELISA applications. Recognizes human, mouse, and rat targets. Supplied as liquid form, 1 mg/mL, purified by Protein A. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Dopamine D2 Receptor (amino acids 301–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Dopamine D2 Receptor (DRD2) is involved in neuromodulation of appetitive behaviors and may be associated with alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduced spontaneous movements, resembling Parkinson’s disease. Three alternatively spliced isoforms have been identified. DRD2 is expressed in various brain regions, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and from brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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