
Thermo Fisher Scientific HOXD9 Monoclonal Antibody (OTI2B1), TrueMAB
HOXD9 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에서 1:500~1:2,000으로 사용 가능. Human 시료 반응성. 동결건조 형태로 제공되며 PBS(8% trehalose) 버퍼에 보관. 연구용으로 세포 발달 및 전사 조절 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 109–352 of human HOXD9 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HOXD9 is a sequence-specific transcription factor that is part of a developmental regulatory system providing cells with positional identities along the anterior-posterior axis. It belongs to the homeobox gene family, which encodes highly conserved transcription factors essential for morphogenesis in multicellular organisms.
Mammals possess four similar homeobox gene clusters (HOXA, HOXB, HOXC, HOXD) located on different chromosomes, each containing 9–11 genes arranged in tandem. HOXD9 is located in the 2q31–2q37 region. Deletions of this cluster are associated with severe limb and genital abnormalities. The exact role of this gene remains under investigation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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