Thermo Fisher Scientific TCF12 Monoclonal Antibody (OTI4B5), TrueMAB
TCF12 단백질을 인식하는 Mouse Monoclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 최적화되어 있으며, Lyophilized 형태로 제공됩니다. 고순도 Affinity chromatography 정제, PBS buffer에 trehalose 포함, 연구용 전용 제품입니다.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B5 |
| Immunogen | Full length human recombinant protein of human TCF12 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TCF12 (also known as HTF4) is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG.
It is expressed in skeletal muscle, thymus, B- and T-cells, and regulates lineage-specific gene expression via heterodimer formation with other bHLH E-proteins.
TCF12, together with E2A, blocks thymocyte proliferation before pre-TCR expression and is essential for proper T cell differentiation.
It also plays a critical role in the development of invariant natural killer T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: CF809668_TCF12_Q99081-1_House_mouse.svg, CF809668_TCF12_Q99081-1_House_mouse_PDP.jpeg)
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