Thermo Fisher Scientific Phospho-Histone H2A (Ser2) Polyclonal Antibody
Histone H2A의 Ser2 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 인산화된 H2A 단백질의 내인성 수준 검출에 사용. 액상 형태로 -20°C 보관, 1 mg/mL 농도.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Histone H2A (Accession P04908), corresponding to amino acid residues around phosphorylated Ser2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817350 |
Product Specific Information
This antibody detects endogenous levels of Histone H2A only when phosphorylated at Ser2.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction into higher-order structures. This gene is intronless, encodes a member of the histone H4 family, and is located in the large histone gene cluster on chromosome 6. Transcripts from this gene lack polyA tails but contain a palindromic termination element.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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