Thermo Fisher Scientific ALX3 Polyclonal Antibody
ALX3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ALX3 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human ALX3 (UniProt ID: O95076-1, antigen range: 197–220, antigen length: 343 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635229 |
Product Specific Information
This antibody detects endogenous levels of total ALX3 protein.
Target Information
Aristaless-related genes are a group of paired-related homeobox genes involved in vertebrate embryogenesis regulation. The homeodomain transcription factor ALX3 is expressed in mouse embryos from 8 days of gestation, mainly in neural crest-derived mesenchyme and lateral plate mesoderm. In humans and mice, ALX3 expression is predominant in brain tissue. The Alx3 gene, located on chromosome 1p23–p13, encodes a 343 amino acid protein. Preferential methylation of Alx3 occurs in advanced-stage neuroblastoma, repressing ALX3 expression, which can be restored by the methylation inhibitor 5-aza-2'-deoxycytidine. Alx3 (-) mice show no distinct phenotype, but Alx3/Alx4 double mutants exhibit severe craniofacial abnormalities, including cleft nasal regions and malformed neural crest-derived skull structures.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.