
Thermo Fisher Scientific CARKL Polyclonal Antibody
CARKL 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상형 항체로, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SHPK (Accession Q9UHJ6), corresponding to amino acid residues A33–S83 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850708 |
Product Specific Information
This antibody detects endogenous levels of total CARKL.
Target Information
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting their return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests possible differences in substrate, cofactor, or kinetic properties. The gene resides in a region commonly deleted in cystinosis patients, suggesting a potential role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, which are frequently involved in chromosomal rearrangements.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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