Thermo Fisher Scientific Ezrin Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Ezrin 폴리클로날 항체. Rabbit IgG 기반으로 인간, 마우스, 랫드 등 반응. 항원 친화 크로마토그래피로 정제되었으며, ezrin 유사 단백질과 교차 반응 없음. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
| Flow Cytometry (Flow) | 1:50 | - |
| Immunoprecipitation (IP) | 1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human ezrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 12 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977904 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with ezrin homologues such as radixin and moesin.
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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