Thermo Fisher Scientific PPP2R1A Polyclonal Antibody
PPP2R1A 단백질 인식용 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot, ICC/IF, Flow cytometry에 적합. PP2A A subunit의 C-말단 합성 펩타이드로 면역화. 비교활성 없음, 항원 친화 크로마토그래피로 정제된 액상 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the carboxy terminus of human PP2A A subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 33 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981701 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other PP2A subunits.
Target Information
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12, it promotes dephosphorylation of microtubule-associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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