Thermo Fisher Scientific IL-9 Monoclonal Antibody (222604)
마우스 IL-9를 특이적으로 인식하는 Rat IgG2a 형 단클론 항체로, Western blot 및 Flow cytometry에 사용 가능. 인간 IL-9과 교차 반응 없음. 단백질 A/G로 정제되었으며, Lyophilized 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 222604 |
| Immunogen | Sf21-derived recombinant mouse IL-9 (Gln19–Pro144) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609397 |
Product Specific Information
- In Western blots, no cross-reactivity with recombinant human IL-9 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes.
IL-9 regulates many cell types involved in Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells.
Mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein (~14 kDa).
Native mouse IL-9 is heavily glycosylated.
TGF-β is known to influence differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, promoting Th9 cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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