Thermo Fisher Scientific NKG2A Recombinant Rabbit Monoclonal Antibody (BLR290L)
Human NKG2A 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot 및 IHC(P)에서 검증됨. HEK293F 발현 시스템에서 생산되며, 1 mg/mL 농도의 액상 형태로 제공. FFPE 조직에서 citrate buffer(pH 6.0) 항원 회복 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR290L |
| Immunogen | Peptide representing a region between residue 0 and 50 of Human NKG2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity.
The protein encoded by this gene belongs to the killer cell lectin-like receptor family (NKG2 family), a group of transmembrane proteins preferentially expressed in NK cells.
This family is characterized by a type II membrane orientation and a C-type lectin domain. The protein forms a complex with KLRD1/CD94 and is involved in recognizing MHC class I HLA-E molecules in NK cells.
The NKG2 gene family forms a receptor gene cluster on chromosome 12, and four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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