Thermo Fisher Scientific BMP8B Monoclonal Antibody (6D6)
BMP8B 단백질을 인식하는 Thermo Fisher Scientific의 6D6 클론 마우스 단일클론 항체. Western blot 및 ELISA에 적합하며, 인간 BMP8B에 반응. 액상 형태, 보존제 없음, -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D6 |
| Immunogen | BMP8B (NP_001711, 274 a.a. ~ 362 a.a) 부분 재조합 단백질 (GST tag 포함, GST tag MW 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KKSNELPQAN RLPGIFDDVH GSHGRQVCRR HELYVSFQDL GWLDWVIAPQ GYSAYYCEGE CSFPLDSCMN ATNHAILQSL VHLMMPDAV
Target Information
BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors, leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.
The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer.
BMP-8B may have arisen from a gene duplication event, and its gene duplicate is also present on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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