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Thermo Fisher Scientific BMP8B Monoclonal Antibody (6D6)
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Thermo Fisher Scientific BMP8B Monoclonal Antibody (6D6)

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BMP8B 단백질을 인식하는 Thermo Fisher Scientific의 6D6 클론 마우스 단일클론 항체. Western blot 및 ELISA에 적합하며, 인간 BMP8B에 반응. 액상 형태, 보존제 없음, -20°C 보관. 연구용으로만 사용.

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pk
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Thermo Fisher Scientific H00000656-M01A BMP8B Monoclonal Antibody (6D6) 200 ul pk판매 단위 pk
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518,100원VAT 포함 569,910원

Thermo Fisher Scientific · Thermo Fisher Scientific BMP8B Monoclonal Antibody (6D6)

Applications

Western Blot (WB)

  • Tested Dilution: 1:500–1:1,000

ELISA

  • Tested Dilution: 1:500–1:1,000

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Clone 6D6
Immunogen BMP8B (NP_001711, 274 a.a. ~ 362 a.a) 부분 재조합 단백질 (GST tag 포함, GST tag MW 26 kDa)
Conjugate Unconjugated
Form Liquid
Concentration See Label
Storage Buffer Ascites
Contains No preservative
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows:
KKSNELPQAN RLPGIFDDVH GSHGRQVCRR HELYVSFQDL GWLDWVIAPQ GYSAYYCEGE CSFPLDSCMN ATNHAILQSL VHLMMPDAV

Target Information

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors, leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.
The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer.
BMP-8B may have arisen from a gene duplication event, and its gene duplicate is also present on chromosome 1.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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