Thermo Fisher Scientific JunD Recombinant Rabbit Monoclonal Antibody (2H8L8)
Recombinant rabbit monoclonal antibody targeting human JunD; validated for WB and ICC/IF. High specificity and lot-to-lot consistency with in vitro expression system. Suitable for research on transcriptional regulation and stress response.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2H8L8 |
| Immunogen | 3 synthetic peptides corresponding to human JunD (aa 2–16, 132–149, 299–313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532499 |
Product Specific Information
This antibody is predicted to react with Dog, Bovine, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
JunD is a transcription factor encoded by the JunD gene. Its activity is modulated by phosphorylation in response to cellular stress via the c-Jun N-terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family. Jun proteins can form dimers with Fos, ATF, and CREB family transcription factors to form the AP-1 complex, which regulates genes involved in growth, proliferation, differentiation, and apoptosis. JunD also plays an important role in metabolism through modulation of the IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: 701669_JunD_P17535-1_Rabbit.svg, 701669_JunD_P17535-1_Rabbit_PDP.jpeg)
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