
Thermo Fisher Scientific RASSF5 Monoclonal Antibody (OTI1C6), TrueMAB
인간 RASSF5 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. 마우스 IgG2b 아이소타입의 TrueMAB 포맷. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 종양 억제 단백질 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Full length human recombinant protein of RASSF5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RASSF5 gene belongs to the Ras association domain family and functions as a tumor suppressor. It is often inactivated in various cancers. The encoded protein localizes to centrosomes and microtubules, binding to GTP-activated forms of Ras, Rap1, and other small GTPases.
It regulates lymphocyte adhesion and suppresses cell growth in response to activated Ras or Rap1. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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