Thermo Fisher Scientific VNN1 Polyclonal Antibody
Thermo Fisher Scientific의 VNN1 Polyclonal Antibody는 인간 VNN1 단백질을 인식하는 토끼 유래 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 232–457 of vanin-1 (Uniprot ID: O95497) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11153630 |
Product Specific Information
- Recommended positive controls: H1299, HeLa, HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes.
GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells.
Vanin-1 acts as a pantetheinase enzyme, catalyzing pantetheine hydrolysis for vitamin B5 recycling and generating cysteamine, a potent antioxidant.
In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, aiding in cell migration.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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