Thermo Fisher Scientific CD298 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: A431, HeLa
• Predicted reactivity: Rabbit (81%), Rhesus Monkey (99%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, and to the subfamily of Na⁺/K⁺-ATPases. Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport of organic and inorganic molecules, and electrical excitability of nerve and muscle.
This enzyme consists of two subunits: a large catalytic alpha subunit and a smaller glycoprotein beta subunit. The beta subunit regulates the number of sodium pumps transported to the plasma membrane through assembly of alpha/beta heterodimers. The glycoprotein subunit of Na⁺/K⁺-ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit, and a pseudogene exists on chromosome 2.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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