Thermo Fisher Scientific RGS4 Polyclonal Antibody
RGS4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간과 랫트 반응성, 항원 친화 크로마토그래피로 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–205 of RGS4 (Uniprot ID: P49798) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155787 |
Product Specific Information
- Recommended positive controls: Raji, mouse cerebellum, rat brain
- Predicted reactivity: Mouse (95%), Rat (96%), Pig (95%), Rabbit (95%), Sheep (96%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins.
RGS proteins deactivate G protein subunits of the Gi alpha, Go alpha, and Gq alpha subtypes, driving them into their inactive GDP-bound forms.
RGS4 belongs to this family and shares a conserved 120-amino acid RGS domain.
RGS4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4.
It negatively regulates signaling at or upstream of the heterotrimeric G protein level and is localized in the cytoplasm.
Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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