
Thermo Fisher Scientific AMPK gamma-2 Polyclonal Antibody
AMPK gamma-2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 사용 가능. Human과 Mouse에 반응하며 높은 특이성과 순도를 가진 항원 친화 크로마토그래피 정제 제품. 연구용으로 에너지 대사 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 386–569 of AMPK gamma 2 (Uniprot ID# Q9UGJ0) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152969 |
Product Specific Information
- Recommended positive controls: HepG2, Mouse brain
- Predicted reactivity: Mouse (98%), Rat (97%), Chicken (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes.
AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This gene encodes a protein with four cystathionine beta-synthase domains. Mutations are associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease, and cardiac hypertrophy. Alternate splice variants encoding different isoforms have been characterized.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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