Thermo Fisher Scientific Phospho-Cdc25C (Ser216) Polyclonal Antibody
인간 CDC25C의 인산화 Ser216 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며 HeLa 세포에서 양성 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human CDC25C (phospho Ser216). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2736358 |
Product Specific Information
- Positive Control: HeLa
- Predicted Reactivity: Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is evolutionarily conserved and plays a key role in regulating cell division. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It dephosphorylates cyclin B-bound CDC2 (CDK1), triggering entry into mitosis, and is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though many are not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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