Thermo Fisher Scientific STAT5 Polyclonal Antibody
STAT5 단백질을 표적하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 4°C 단기 또는 -20°C 장기 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide surrounding the C-terminus of STAT5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse liver
- Cellular location: Nuclear
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, forming homo- or heterodimers that translocate to the nucleus to act as transcription activators.
This protein mediates responses to ligands such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and various growth hormones. Activation in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and is essential for tumorigenesis. The mouse counterpart induces BCL2L1/BCL-X(L) expression, suggesting an anti-apoptotic role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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