Thermo Fisher Scientific Phospho-FGFR2 (Ser782) Polyclonal Antibody
FGFR2 단백질의 Ser782 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 사람, 생쥐, 랫트 반응성. PBS/glycerol 완충액에 보존되며 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FGFR2 (Accession P21802), corresponding to amino acid residues around phosphorylated Ser782. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817538 |
Product Specific Information
This antibody detects endogenous levels of FGFR2 only when phosphorylated at Ser782.
Target Information
FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. FGFR family members are implicated in diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy. Mutations in FGFR2 are associated with syndromes including Crouzon, Pfeiffer, Craniosynostosis, Apert, Jackson-Weiss, Beare-Stevenson cutis gyrata, Saethre-Chotzen, and other syndromic craniosynostoses. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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