Thermo Fisher Scientific Phospho-EphB6 (Tyr651) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Product Specific Information

Antibody detects endogenous levels of EPHB6 only when phosphorylated at Tyr651.

Target Information

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.
Based on their structures and sequence relationships, ephrins are divided into two classes:

• Ephrin-A (EFNA): Anchored to the membrane by a glycosylphosphatidylinositol linkage
• Ephrin-B (EFNB): Transmembrane proteins

The Eph family of receptors is divided into two groups based on extracellular domain sequence similarity and ligand binding affinity.
Ephrin receptors form the largest subgroup of the receptor tyrosine kinase (RTK) family.
The ephrin receptor encoded by this gene lacks the kinase activity typical of most RTKs and binds to ephrin-B ligands.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.