Thermo Fisher Scientific Phospho-EphB6 (Tyr651) Polyclonal Antibody
Phospho-EphB6 (Tyr651) 특이적 인식 항체로 인간, 마우스, 랫트 반응성. Western blot에 최적화된 rabbit polyclonal antibody. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB6 (Accession O15197), corresponding to amino acid residues around phosphorylated Tyr651 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817535 |
Product Specific Information
Antibody detects endogenous levels of EPHB6 only when phosphorylated at Tyr651.
Target Information
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.
Based on their structures and sequence relationships, ephrins are divided into two classes:
- Ephrin-A (EFNA): Anchored to the membrane by a glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): Transmembrane proteins
The Eph family of receptors is divided into two groups based on extracellular domain sequence similarity and ligand binding affinity.
Ephrin receptors form the largest subgroup of the receptor tyrosine kinase (RTK) family.
The ephrin receptor encoded by this gene lacks the kinase activity typical of most RTKs and binds to ephrin-B ligands.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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