Thermo Fisher Scientific KSHV ORF62 Monoclonal Antibody (5B7B6)
KSHV ORF62 단백질을 특이적으로 인식하는 Mouse IgM 단일클론 항체로, WB, IHC, ELISA 등 다양한 응용에 적합. 비결합형 액상 형태로 제공되며, 바이러스 샘플에 반응. 장기 보관 시 -20°C에서 안정적으로 저장 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B7B6 |
| Immunogen | Purified recombinant fragment of human KSHV ORF62 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10984866 |
Product Specific Information
MA5-14770 targets KSHV ORF62 in indirect ELISA, IHC, and WB applications and shows reactivity with virus samples.
The immunogen is a purified recombinant fragment of human KSHV ORF62 expressed in E. coli.
Target Information
Kaposi’s sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and is closely linked to Kaposi’s sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman’s disease.
The KSHV genome (165–170 kb) contains at least 88 open reading frames. Five major proteins are likely involved in HHV-8 capsid assembly: a protease (ORF17), the major capsid protein (ORF25), and three smaller capsid proteins (ORF62, ORF26, ORF65).
Structural studies suggest the KSHV triplex is composed of a monomer of ORF62 and a dimer of ORF26, analogous to HSV-1 and HCMV triplex structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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