Thermo Fisher Scientific CUL3 Polyclonal Antibody
Rabbit polyclonal antibody against human CUL3 for Western blot applications. Recognizes human, mouse, and rat. Lyophilized form, reconstitutable to 500 µg/mL. Affinity purified, unconjugated, and suitable for research use only.
- 카탈로그번호
- PA5114434
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human Cullin 3 (426–444 aa, DVFERYYKQHLARRLLTNK) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2884866 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Cullin 3 (CUL3) is a member of the human cullin gene family (CUL1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc53 gene.
CUL1 forms a complex with human p19 skp1 and F-box protein p45 skp2, acting as a ubiquitin ligase to regulate G1 cell cycle proteins.
In contrast, CUL2 associates with the Elongin complex (Elongin C, Elongin B, and VHL) forming an inactive transcriptional elongation complex, though its function remains unclear.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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