Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (rKRT14/7269)
사람 세포 반응성의 단클론성 항체로, Cytokeratin 14을 표적하여 편평세포암 등 상피세포 마커 연구에 활용. 파라핀 또는 PFA 고정 조직 면역조직화학에 적합하며, 단백질 A/G 정제된 액상 형태. 연구용으로만 사용.
- 카탈로그번호
- 3861-MSM29-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (rKRT14/7269)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rKRT14/7269 |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified. Biochemically, CKs are classified into two groups: type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and typically exists in combination with keratin 5. It helps distinguish stratified epithelial cells from simple epithelial cells and is useful in identifying squamous cell carcinomas. Moreover, keratin 14 is considered a prognostic marker in breast carcinomas. Both acidic and basic keratin family members are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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