Thermo Fisher Scientific c-Jun Monoclonal Antibody (C.238.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

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Immunohistochemistry (Paraffin) (IHC (P))

1:150-1:600

-

Immunocytochemistry (ICC/IF)

1:200-1:400

-

Immunoprecipitation (IP)

1:50

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ChIP assay (ChIP)

1:50

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Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

C.238.2

Immunogen

GST-c-Jun protein corresponding to the amino-terminal sequence of human c-Jun if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:c-Jun,uniProtId:P05412-1,ncbiNodeId:9606,antigenRange:1,antigenLength:331,antigenImageFileName:MA5-15172_c-Jun_P05412-1_Rabbit.svg,antigenImageFileNamePDP:MA5-15172_c-Jun_P05412-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

48 µg/mL

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10979794

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5-TGA\[CG\]TCA-3. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.