Thermo Fisher Scientific c-Jun Monoclonal Antibody (C.238.2)
Thermo Fisher Scientific의 c-Jun Monoclonal Antibody (C.238.2)는 인간, 생쥐, 원숭이, 쥐에 반응하는 고품질 항체입니다. Western blot, IHC, ICC/IF, IP, ChIP 등 다양한 응용에 적합하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피로 정제되어 연구용으로 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150–1:600 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:400 | - |
| Immunoprecipitation (IP) | 1:50 | View 1 publication |
| ChIP assay (ChIP) | 1:50 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.238.2 |
| Immunogen | GST-c-Jun protein corresponding to the amino-terminal sequence of human c-Jun |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 48 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10979794 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. It is involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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