Thermo Fisher Scientific Phospho-VEGF Receptor 2 (Tyr1175) Monoclonal Antibody (S.657.3)
Phospho-VEGF Receptor 2 (Tyr1175) 단일클론 항체로, 인간 및 마우스 시료에 반응합니다. Western blot에 최적화되어 있으며, 고순도의 Affinity chromatography로 정제되었습니다. -20°C 보관, 연구용 전용입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S.657.3 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1175 of human VEGF receptor-2 (FLK1, VEGF Receptor 2, UniProt ID: P35968-1, antigen range: 1175–1356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 173 µg/mL |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10976962 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity. It is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of VEGF, known as the kinase insert domain receptor. Its signaling and trafficking are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase. Mutations in FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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