Thermo Fisher Scientific RNF43 Polyclonal Antibody
Thermo Fisher Scientific RNF43 Polyclonal Antibody는 인간 RNF43 단백질을 표적으로 하는 토끼 IgG 폴리클로날 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. Wnt 신호 경로 연구 및 종양 억제 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: Not specified
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human RNF43 recombinant protein (Position: G24–Y197) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2747045 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis, and subsequent degradation of Wnt receptor complex components Frizzled.
Acts on both canonical and non-canonical Wnt signaling pathways.
Functions as a tumor suppressor in the intestinal stem cell zone by inhibiting Wnt signaling, thereby restricting the size of the intestinal stem cell zone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-79930_RNF43_Q68DV7-1_Rabbit.svg)
(이미지: PA5-79930_RNF43_Q68DV7-1_Rabbit_PDP.jpeg)
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