Thermo Fisher Scientific VEGF Receptor 2 Monoclonal Antibody (KDR-2 or 260.4), Biotin
VEGF Receptor 2(KDR-2 or 260.4) 단클론 항체, Biotin 결합형. 인간 VEGFR2에 특이적이며 VEGFR1, VEGFR3, PDGFR1에는 반응하지 않음. Western blot과 유세포분석에 적합. 고순도 정제, 4°C 단기 보관 또는 -20°C 장기 보관.
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Thermo Fisher Scientific VEGF Receptor 2 Monoclonal Antibody (KDR-2 or 260.4), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KDR-2 or 260.4 |
| Immunogen | Recombinant, extracellular, human VEGF receptor 2 protein fragment |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_561912 |
Additional Formats
Product Specific Information
This antibody does not detect VEGFR1, VEGFR3, or PDGF Receptor 1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity in vitro. It is expressed early in development by endothelial cell precursors.
FLK1 (VEGF Receptor 2) encodes one of the two receptors of VEGF, known as kinase insert domain receptor. Its signaling and trafficking are regulated by multiple factors including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase.
Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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