Thermo Fisher Scientific Blimp-1 Monoclonal Antibody (3H2-E8), DyLight 550

Applications and Tested Dilutions

Product Specifications

Available Formats

• Unconjugated
• DyLight 488
• DyLight 650
• HRP
• Request custom conjugation

Product Specific Information

• In Western Blot, this antibody recognizes a band at approximately 98 kDa and may also detect one at ~80 kDa (beta form).
• Antigen retrieval (EDTA buffer, microwave) is recommended prior to IHC on paraffin tissues.
• This antibody does not immunoprecipitate.
• For IHC and ICC/IF, a dilution of 1:200 with tyramide amplification is recommended; demonstrates nuclear staining.
• Suggested positive control: P3X (murine plasmocytoma) cell lysates.

Target Information

Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein containing five zinc fingers at its carboxy terminus. It acts as a transcriptional repressor essential for the terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in terminally differentiated epithelial cells, retinal neurons, and other lineage cells. It also plays a role in repressing beta-interferon (IFN-β) and c-myc gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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