Thermo Fisher Scientific hnRNP H1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Positive test controls: Rat testis, Rat brain
• Localization: Nucleus, nucleoplasm

Immunogen sequence:
VRTHYDPPRK LMAMQRPGPY DRPGAGRGYN SIGRGAGFER MRRGAYGGGY GGYDDYNGYN DGYGFGSDRF GRDLNYCFSG MSDHRYGDGG STFQSTTGHC VHMRGLPYRA TENDIYNFFS PLNPVRVHIE IGPDGRVTGE ADVEFATHED AVAAMSKDKA NMQHRYVELF LNSTAGASGG AYEHRYVELF LNSTAGASGG AYGSQMMGGM GLSNQSSYGG PASQQLSGGY GGGYGGQSSM SGYDQVLQEN SSDFQSNIA

Target Information

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
While all hnRNPs are present in the nucleus, some may shuttle between the nucleus and cytoplasm. The protein encoded by this gene has three quasi-RRM domains that bind RNA and is similar to HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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