Thermo Fisher Scientific hnRNP H1 Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP H1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 WB, IHC, ICC, ELISA에 적합합니다. Rabbit IgG 폴리클로날 항체로, 핵 및 핵질에서 발현되는 hnRNP H1 단백질 검출에 사용됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 191–449 of human HNRNPH1 (NP_005511.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914536 |
Product Specific Information
- Positive test controls: Rat testis, Rat brain
- Localization: Nucleus, nucleoplasm
Immunogen sequence:
VRTHYDPPRK LMAMQRPGPY DRPGAGRGYN SIGRGAGFER MRRGAYGGGY GGYDDYNGYN DGYGFGSDRF GRDLNYCFSG MSDHRYGDGG STFQSTTGHC VHMRGLPYRA TENDIYNFFS PLNPVRVHIE IGPDGRVTGE ADVEFATHED AVAAMSKDKA NMQHRYVELF LNSTAGASGG AYEHRYVELF LNSTAGASGG AYGSQMMGGM GLSNQSSYGG PASQQLSGGY GGGYGGQSSM SGYDQVLQEN SSDFQSNIA
Target Information
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
While all hnRNPs are present in the nucleus, some may shuttle between the nucleus and cytoplasm. The protein encoded by this gene has three quasi-RRM domains that bind RNA and is similar to HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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