Thermo Fisher Scientific Human CX3CR1 Synthetic Peptide
Human CX3CR1 단백질의 세포외 루프 도메인에 해당하는 15개 아미노산 합성 펩타이드입니다. CX3CR1 항체의 블로킹 실험에 사용됩니다. 고순도 정제 제품으로 PBS/BSA 버퍼에 용해되어 있으며, 연구용으로만 사용 가능합니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the extracellular loop domain of human CX3CR1.
PEP-0060 can be used as a blocking peptide with polyclonal antibody PA5-19935.
Target Information
CX3CR1 is one of the chemokine receptors required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven-transmembrane protein was identified as the receptor for the transmembrane molecule fractalkine and renamed CX3CR1. CX3CR1 serves as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine. It mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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