Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser221) Recombinant Rabbit Monoclonal Antibody (MEK12S221-D3), APC
APC 형광 표지된 재조합 Rabbit Monoclonal 항체로 MEK1/MEK2의 Ser221 인산화 형태를 검출. 인간 및 생쥐 시료에 반응. Flow Cytometry에 최적화. Protein A/G로 정제되어 BSA 및 sodium azide 포함 PBS 용액으로 제공.
- 카탈로그번호
- MA537079
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser221) Recombinant Rabbit Monoclonal Antibody (MEK12S221-D3), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEK12S221-D3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser221 of human phospho MEK1/2 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897014 |
Additional Formats
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In the brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002). Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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