Thermo Fisher Scientific CCR6 Monoclonal Antibody (53103.111)

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

25 µg/mL

-

Flow Cytometry (Flow)

1 µg for 10^6 cells

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

53103.111

Immunogen

Human CCR6 transfected NSO mouse myeloma cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_557991

Product Specific Information

Recommended positive controls: human PBMCs.

Endotoxin level is less than 10 ng per mg antibody as determined by the LAL method.

Target Information

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.