Thermo Fisher Scientific CCR6 Monoclonal Antibody (53103.111)
CCR6 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, 인간 PBMCs에서의 IHC(F) 및 유세포분석(Flow)에 적합합니다. 비접합(Unconjugated) 형태로 제공되며, 낮은 엔도톡신 수준을 보장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 25 µg/mL |
| Flow Cytometry (Flow) | 1 µg for 10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 53103.111 |
| Immunogen | Human CCR6 transfected NSO mouse myeloma cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_557991 |
Product Specific Information
- Recommended positive controls: human PBMCs
- Endotoxin level: less than 10 ng per mg antibody (determined by the LAL method)
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. Its ligand is macrophage inflammatory protein 3 alpha (MIP-3α).
CCR6 plays a key role in B-lineage maturation and antigen-driven B-cell differentiation, and may regulate migration and recruitment of dendritic and T cells during inflammatory and immune responses. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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