Thermo Fisher Scientific Phospho-PLD1 (Ser561) Polyclonal Antibody
PLD1 단백질의 Ser561 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot 및 IHC(P) 응용에 적합. 사람, 생쥐, 랫트 반응성. 고순도 정제 및 안정적인 액상 형태로 제공.
- 카탈로그번호
- PA5105636
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLD1 (Accession Q13393), corresponding to amino acid residues around phosphorylated Ser561 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817064 |
Product Specific Information
Antibody detects endogenous levels of PLD1 only when phosphorylated at Ser561.
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-105636_PLD1_Q13393-1_Rabbit.svg, PA5-105636_PLD1_Q13393-1_Rabbit_PDP.jpeg)
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