Thermo Fisher Scientific Napsin A Monoclonal Antibody (ZY397)
인간 Napsin A 단백질을 인식하는 마우스 단클론 항체로 폐선암 등 인체 조직 연구에 적합. Western blot 및 IHC(파라핀) 응용 가능. Protein A로 정제된 액상 형태이며 안정화 PBS 버퍼에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Napsin A Monoclonal Antibody (ZY397)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY397 |
| Immunogen | Recombinant protein Napsin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human lung adenocarcinoma
- Cellular location: Secreted
Target Information
Napsin 1 is an aspartic protease primarily expressed in the lung, and also found in kidney and metastatic carcinomas. It processes surfactant protein B in healthy pulmonary and renal tissues but is dysregulated in carcinogenesis. Napsin evaluation is useful for identifying various cancers and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin serves as a specific biomarker for carcinoma type differentiation. It is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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