Thermo Fisher Scientific Myeloid Marker Monoclonal Antibody (BM2)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1-1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

BM2

Immunogen

PWM-stimulated human PBL if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYADM,uniProtId:Q96S97-1,ncbiNodeId:9606,antigenRange:1-322,antigenLength:322,antigenImageFileName:606-060_MYADM_Q96S97-1_House_mouse.svg,antigenImageFileNamePDP:606-060_MYADM_Q96S97-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive control: Bone marrow

Cellular location: Myeloid cells.

Target Information

MYADM, belonging to the MAL family, is a 322-amino acid protein having 7 hydrophobic transmembrane domains, several potential consensus sites for phosphorylation and sequence homology with the T-cell differentiation protein MAL and plasmolipin. It shares 75.8% sequence identity with mouse in the transmembrane regions and is associated with differentiation of hematopoietic cells or acute promyelocytic leukemia cells. Its expression is up-regulated in NB4 cells induced by all-trans retinoic acid whereas down regulation inhibits colony formation of bone marrow cells. MYADM could serve as a new marker for hematopoietic differentiation and is a target for diagnostic, prognostic and/or therapeutic interventions. It is known to express widely in brain and pancreatic islet cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.