Thermo Fisher Scientific ACOX1 Recombinant Rabbit Monoclonal Antibody (003)

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Human ACOX1/AOX.

Target Information

The protein encoded by this gene is the first enzyme of the fatty acid β-oxidation pathway, catalyzing the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, producing hydrogen peroxide. Defects in this gene cause pseudoneonatal adrenoleukodystrophy, characterized by accumulation of very long-chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.